課程名稱 |
人腦映像方法 Human Brain Mapping Methods |
開課學期 |
102-1 |
授課對象 |
工學院 醫學工程學研究所 |
授課教師 |
林發暄 |
課號 |
Biomed7086 |
課程識別碼 |
548 M1300 |
班次 |
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學分 |
3 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期三5,6,7(12:20~15:10) |
上課地點 |
共406 |
備註 |
總人數上限:20人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1021Biomed7086 |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
Course Schedule
1 Introduction
2 Functional neural systems
2.1 Cellular electrophysiology
2.2 System neuroanatomy
3 Neurovascular coupling
4 Electrophysiological measurements (Magnetoencephalography)
4.1 Physiological origin
4.2 Forward problem
4.3 Inverse problem
5 Hemodynamic measurements (functional MRI)
5.1 Physiological origin
5.2 Contrast mechanisms (BOLD, flow/volume)
5.3 Experiment design
5.4 Pre-processing
5.5 Statistical analysis
6 Other measurements
6.1 Structure
6.2 Metabolism (MR spectroscopy)
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課程目標 |
This course focus on the introduction of modern non-invasive human neuroimaging facilities, including but not limited to, structural magnetic resonance imaging (MRI), functional magnetric resonance imaging (fMRI), MR spectroscopic imaging, and magnetocephalography (MEG). We will also include a very brief introduction to the cellular and system level neuroscience before presenting individual imaging methods. We wish to bring you a general concept of neuroimaging methods as well as their features, advantages, and limitations. |
課程要求 |
*preferred backgounds* MRI physics, electromagnetics, system neuroscience, signal processing, statistics, linear algebra |
預期每週課後學習時數 |
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Office Hours |
另約時間 |
指定閱讀 |
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參考書目 |
Brain Mapping: The Methods (ISBN: 0126925402)
Arthur W. Toga, John C. Mazziotta
Academic Press; 1st edition (January 15, 1996)
Principles of Neural Science (ISBN: 0838577016)
Eric R. Kandel, James H. Schwartz, Thomas M. Jessell
McGraw-Hill Medical; 4 edition (January 5, 2000)
An Introduction to Functional Magnetic Resonance Imaging: Principles and
Techniques (ISBN: 0521002745)
R. B. Buxton
Cambridge University Press; Har/Cdr edition (December 15, 2001)
Functional Magnetic Resonance Imaging (ISBN: 0878932887)
Scott A. Huettel, Allen W. Song, Gregory McCarthy
Sinauer Associates; Har/Cdr edition (April 1, 2004)
The Human Brain: An Introduction to Its Functional Anatomy (ISBN: 0323013201)
John Nolte
Mosby; 5 edition (January 15, 2002) |
評量方式 (僅供參考) |
No. |
項目 |
百分比 |
說明 |
1. |
course participation |
30% |
|
2. |
quizes |
30% |
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3. |
final report |
40% |
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週次 |
日期 |
單元主題 |
第1週 |
9/11 |
introduction
history
time and space |
第2週 |
9/18 |
system neuroanatomy |
第3週 |
9/25 |
system neuroanatomy
magnetic resonance imaging |
第4週 |
10/2 |
magnetic resonance imaging |
第5週 |
10/9 |
magnetic resonance imaging |
第6週 |
10/16 |
echo-planar imaging and BOLD fMRI |
第7週 |
10/23 |
hemodynamic measurements: perfusion |
第8週 |
10/30 |
metabolic measurements: MR spectroscopy and spectroscopic imaging |
第9週 |
11/6 |
diffusion MRI and structural connectivity |
第10週 |
11/13 |
Transcranial magnetic stimulation (TMS) |
第11週 |
11/20 |
magnetoencephalography (MEG) |
第12週 |
11/27 |
final report |
第13週 |
12/4 |
final report |
第14週 |
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期末問卷 (修課人數= 11,問卷回收率= 64%) |
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